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CBD Oil for Alzheimer's Disease

September 24, 2018

CBD Oil for Alzheimer's Disease

There are many things you don’t want to forget in life, but forgetting about your family and loved ones is by far the very worst.

Alzheimer’s disease is a serious, chronic, neurodegenerative disease wherein sufferers experience degradation in their brain functions. The condition is responsible for 60-70% of all cases of dementia, and is a serious risk to all elderly people. Its causes are poorly understood, and it completely lacks any kind of known treatment or reversal. For these reasons, its appearance is almost completely random and incomprehensible.

However, doctors do have ways to help mitigate the symptoms, as well as improve the quality of life among those who suffer from the condition. One of the methods that has been popping up increasingly in recent years is cannabidiol, or CBD oil. Before we get looking at CBD oil for Alzheimer’s disease though, and why more and more doctors are recommending it as a potential treatment option, let’s take a look at what Alzheimer’s actually is.

What is Alzheimer’s Disease?

The singularly awful part of Alzheimer’s disease is that it develops slowly. Its causes are not known, but its progression is extremely slow and difficult to notice.

To start with, the sufferer will begin to experience lapses in memory, problems with speech or language, and perhaps most well known (and usually the point at which a diagnosis is made), occasional confusion and subsequent irritation over seemingly nothing.

The reason Alzheimer’s disease develops is almost completely unknown, but we do at least understand some of the processes that are associated with its initiation.

Alzheimer’s disease is characterized by a loss of neurons and synapses in the cerebral cortex, which causes atrophy of the brain and generally results in diminished brain capacity.

Essentially, the brain undergoes a sharp decline in mental ability due to the slow loss of neurons. We are not yet able to identify a step in the process of the declining Alzheimer’s brain to actually stop the disease from progressing, however.

Brain scans of an Alzheimer’s disease patient reveal that the amyloid plaques are dense, with cellular material coating it thickly outside the neurons. When compared to an image of a healthy brain, the sharp definitions of the brain are thick and muted, betraying the cellular degeneration that occurs within.

Additionally, the existence of Lewy bodies is exceedingly common within Alzheimer’s disease brains, which are generally caused by an oxidation effect on the brain cells. These can also lead to the development of Parkinson’s disease, another serious degenerative disease that results in motor loss.

Overall, Alzheimer’s is a particularly terrifying disease because of its incomprehensibility; we don’t understand why it starts, we don’t understand how to treat it, and worst of all, it keeps getting worse for the remainder of the sufferer’s life.

There are medications to hopefully delay the degeneration, but these usually do nothing to abate the eventuality of continued deterioration – and ultimately death – other than slightly delaying it.

There has been new research that considers the use of CBD oil as a possible option to help treat Alzheimer’s disease, but what is CBD oil exactly, and should you use it as a practical treatment option?

Why CBD Oil for Alzheimer’s Disease?

CBD oil is a cannabinoid extract from the Cannabis sativa plant. Instead of possessing the psychoactive properties of its more rowdy cousin THC, however, CBD acts as a counterpoint to the narcotic element of cannabis, serving as a potential medicinal compound with no psychoactive effects.

While the medicinal properties of THC are also quite apparent, it is of course marred by its association with getting high. CBD creates no intoxicating effects, but rather works with the body to help improve overall health and immune balance.

When consumed, CBD interacts with the endocannabinoid system, a health system within the body that’s made up of two primary receptors: CB1 and CB2 receptors, each of which interact with the body in different ways.

CB1 receptors are located primarily within the central nervous system and the brain, whereas CB2 receptors exist more generally throughout the body and are primarily responsible for the instigation of cellular regrowth.

CBD oil is simply extracted cannabidiol that is mixed into inert oil so as to provide an easy method of ingestion. Various studies have shown CBD’s potential for helping with a variety of different diseases and conditions, both in their treatment and in their prevention.

However, one of the most recent discoveries is the use of CBD for Alzheimer’s disease. Let’s see how it works, and what the studies are saying.

CBD Oil, Alzheimer’s Disease, and Neurological Effects 

Cannabis has been researched and examined for use with neurological disorders for several years; ever since marijuana was demonstrated to help with epilepsy, researchers have been keen to see what other conditions the drug may be able to help with.

Drs. Georgia Watt and Tim Karl, for example, in their study for the academic journal Frontiers in Pharmacology, explored the potential for CBD to act as a neuroprotective, regenerative medicine in Alzheimer’s patients.

In the study, Watt and Karl focused on CBD’s established anti-inflammatory and antioxidant properties, and what this could mean for Alzheimer’s symptoms.

Research conducted by such as scientists as Carrier et al. in their significant study were some of the first to look at CBD’s remarkable anti-inflammatory properties, but in Watt and Karl’s study, they were more focused on what that it could specifically mean for neurological cells.

The study found that CBD works effectively at reducing reactive gliosis and the neuroinflammatory response within the brain, as well as promote neurogenesis. This essentially means that, while CBD doesn’t necessarily stop Alzheimer’s disease, it may be able to work as an effective medicine to stop the typical neuroinflammatory response.

Additionally, CBD is well known for its ability to encourage healthy cellular growth, so to have Watt and Karl discover that CBD can encourage neurological cells to regrow in a healthy fashion, is immense news for victims of Alzheimer’s that are looking for a safe, natural treatment option.

Perhaps even more importantly, CBD has been shown to reverse and prevent further development of cognitive deficits during animal tests. These cognitive deficits caused by Alzheimer’s disease are some of the chief problems of the early stages of the condition, as the process of gradually losing your mental faculty and intelligence is an utterly terrifying one.

Cellular regeneration is one of the hallmark properties of CBD, famously being used to treat skin conditions like eczema and psoriasis through proper skin cell regeneration. By applying these same properties to the brain, it would appear that CBD could be effective at helping promote healthy brain cell regeneration as well.

Research into the complete potential for CBD to halt Alzheimer’s disease is yet to be properly undertaken, but due to the recent nature in which CBD has entered the public sphere as an acceptable medicine (rather than its association with getting high), our understanding of the compound’s neurological effects are surely primed to increase.

Watt and Karl’s study serves as an excellent demonstration that CBD – as well as combinations of both CBD and THC – require more study and legitimacy as far as treatments for Alzheimer’s disease go.

A great example of this as of yet “unreached potential” is evident in another study, conducted by Lim et al. for the Journal of Clinical Psychopharmacology and Neuroscience. The publication looked at a variety of other studies wherein medicinal cannabis was used to treat mental and neurological conditions, and one of the conditions investigated was Alzheimer’s disease.

Dr. Lim’s study concluded that, of the 24 reports they investigated, cannabis had a definitive role in reducing agitation and possibly repairing the damage suffered by Alzheimer’s disease patients. However, the reports they investigated were rife with poor methodology and incomplete descriptions, which forced them to report that they were unable to come to an adequate conclusion about the role of cannabis for treatment of Alzheimer’s disease.

They did, however, focus on the fact that more studies should be carried out on Alzheimer’s disease and cannabis, with better scientific practices so as to properly determine its therapeutic potential.

Finally, in a study by Eubanks et al., researchers for the Journal of Molecular Pharmaceutics looked at the molecular link between marijuana and Alzheimer’s disease. In the study, researchers noted that cannabinoids competitively inhibit some of the metabolic enzymes that are key pathological markers to the onset of Alzheimer’s disease. Acetylcholinesterase, in particular, is understood to prevent enzyme-induced amyloid peptide aggregation, and it was found that cannabinoids like CBD bind with the site of the enzyme’s creation, thereby impairing its ability to function.

This study was especially significant in terms of validating cannabis as a potential treatment for Alzheimer’s disease, as it appeared to note cannabis’s ability to change the molecular onset of Alzheimer’s disease entirely.

Thus, not only does CBD appear to work with great efficacy at reducing the damage done to the brain through Alzheimer’s disease, it could actively work to stop its creation altogether.

Final Thoughts on CBD Oil for Alzheimer’s Disease

Alzheimer’s disease is a growing health concern throughout the western world; with population groups tending towards older average ages due to increased life expectancies and better medicine, the rate of Alzheimer’s disease diagnoses is expected to triple over the next 50 years.

In light of this horrifying statistic, it is imperative that we undertake as much research and understanding as possible to help diagnose, treat and prevent Alzheimer’s disease.

Thanks to recent legalization efforts undertaken throughout the western world, cannabis is finally becoming well known as an effective medicine, meaning we can begin to look at its use in treating Alzheimer’s disease.

Though there exists comparatively few studies concerning its efficacy, the results so far have reasonably concluded that CBD – as well as cannabinoids in general – can work as an effective treatment of Alzheimer’s disease both through its cellular regenerative properties and in its ability to promote healthier brain cells through anti-oxidative and anti-inflammatory effects.

We still have much to learn about the potential of CBD, but the simple fact is that thousands of people are already using CBD for Alzheimer’s disease with succesful results. With more research and case studies, this amount will hopefully increase to the point where sufferers of Alzheimer’s disease can be more effectively treated and have their quality of life restored to them.

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Jonathan Miller
Jonathan Miller, age 53 is an Ex Railyard Engineer who suffers from chronic back pain and anxiety. Jonathan’s goal was to create an unbiased site that would provide anyone who seeks help in CBD oil as a treatment, with accurate and helpful information.
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Getting Started with CBD Oil

If you suffer from anxiety (like me), depression or pain and are looking to get started with CBD oil, you need information on how to buy CBD oil, or you’re simply looking to learn more about CBD products, you’ve arrived at the right place.

What is CBD?

Cannabidiol, aka CBD, is a compound found in the cannabis plant that has significant medical benefits. CBD can be extracted from two different species of the Cannabis Sativa L plant, which include Cannabis and Hemp. Unlike its rival THC, CBD does not make people feel “stoned” and can actually counteract the psychoactivity of THC.

One of the main advantages of CBD is its non-psychoactive affect making it a great option for people looking for relief from inflammation, anxiety, insomnia, seizures, spasms, and other conditions.
As I mentioned above the primary distinction between Hemp and CBD oil is the part of the plant they are derived from and what parts of the plant are used to create the oil. Hemp oil is typically made from pressing cannabis seeds to extract the fatty oil from within, while some that have mastered the CBD extraction process also use the flowers as they contain high percentages of CBD. CBD oil, on the other hand, is usually made from the flowers of cannabis plant through various extraction methods.

How Does CBD Affect Your Body?

The way marijuana affects your body varies from person to person as it will often depend on genetics, tolerance to the cannabinoids, medical health, DNA, and more. It also depends on the way you consume the CBD, for example, the effects of vaping CBD are far different to smoking it in the form of high-CBD cannabis strains. 

CBD and the way it affects us is still of somewhat a mystery to researchers they still try to figure out how it effects the EndoCannabinoid system. During the previous century, it was discovered that our bodies have receptors within the brain and central nervous system. Specific cannabinoids such as CBD bind to those receptors and activate the EndoCannabinoid System (ECS). This then provides a wide range of psychological and physical benefits helping the body.

Without going into specifics, cannabinoids signal to the body to create endocannabinoids and build more receptors. This helps the body to limit things associated with pain and inflammation, repairs cells and provides a wide range of other health benefits. Unlike other cannabinoids, CBD is thought to be the ultimate anti-inflammatory cannabinoid.

Want to learn more about how CBD works read: How Long Does it Take CBD to Work

Medical Benefits of CBD

There is a misconception as to whether CBD can help treat patients, similar to pharmaceutical medicine, but thanks to the internet and a few different medical studies patients and researchers have been exposing their findings on how CBD oil is helping to cure a wide range of medical conditions.

The most popular story was the one of Charlotte Figi. At the time Charlotte was only 6 years old. As a little girl, she was experiencing over 300 epileptic seizures per week until she was successfully treated by a CBD-rich strain oil, later named Charlotte’s Web.

The high-quality CBD oil, changed her life, helping her to overcome a 6-year battle. Since her story hit the news, CBD and other cannabinoids of the cannabis plant are constantly being researched to understand how they can help to treat different medical conditions. As a matter of fact, CBD has been thought to help treat over 170 medical conditions, among them severe conditions such as Anorexia, Cancer, Arthritis, Depression, Anxiety, Chronic Pain, Insomnia, Glaucoma, multiple sclerosis and PTSD.

Recent studies have even shown that CBD, may cure life-threatening diseases by altering genes. Other studies have proven that it might even be an effective treatment for osteoarthritis and chronic pain.

The way that CBD works is that it interacts with receptors located in different parts of the central nervous system. These receptors are called CB1 and CB2. Both reflect the areas of the brain they interact with such as the limbic system. When taking CBD, this cannabinoid locks in on these receptors and affects the body in different ways. For example, it can help to block the pain caused by specific medical conditions.

While numerous studies have shown promising results, it is important to understand that CBD research is still at premature stages. A 2011 study that researched CBD for fibromyalgia showed extremely promising results. 56 of 112 participants who took CBD in the form of oil saw a great reduction in their symptoms and pain, while those using traditional methods didn’t see hardly any improvement.

Can you Buy CBD if you live in an illegal state?

The process is not cut-&-dry, and but thanks to the Farm Bill of 2014, forms of CBD can now be delivered to your doorstep. Those that live in recreational states can purchase CBD cannabis oil which is high in potency and extremely effective for helping to treat severe medical conditions, while those that live in other states that are not medical or recreational can benefit from CBD hemp oil. CBD Hemp oil is perfect for helping to treat a wide range of conditions including anxiety, depression and acute pain. 

Who is NaturalWellNessCBDOil?

My name is Jonathan, and I’ve created this loving resource that is packed with information about CBD oil. I am growing a community on Facebook and are constantly engaging with different people to help them make more informed decisions. I review products on a daily basis and provide unbiased reviews about some of the top CBD oil manufacturers. All the information on the site is FREE; I only ask that you help to share the information you find on the site with other people that are suffering. 

To your health and happiness.