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CBD Oil for Rheumatoid Arthritis [Understanding Endocannabinoids]

January 8, 2018

CBD Oil for Rheumatoid Arthritis

It’s important to understand that rheumatoid arthritis and osteoarthritis are two significantly different things. While both disorders involve pain and inflammation of the joints, there are important differences with regard to the underlying causes of each.

The most substantial and obvious difference between rheumatoid and osteoarthritis is that rheumatoid (RA) is an autoimmune disorder, while osteo (OA) is a mechanical disorder. Simply put, this means that immune cells (white blood cells) are responsible for the breakdown of connective joint tissue in RA, while breakdown of tissue in OA is the simple result of age, injury, and/or general wear and tear.

Taking this into consideration, the use of CBD oil for rheumatoid arthritis has spiked dramatically in recent years in direct response to new data showing the potential role of the endocannabinoid system in reversing the autoimmune effects of the disease.

In this article, I’ll talk more about the actual physiological effects of RA, and discuss what role CBD oil plays in decreasing the likelihood of potential attacks on healthy joint tissue.

CBD Oil for RA – Understanding more about the disease

In victims who suffer from RA, the synovial fluid within joint areas is targeted and attacked by the body’s own immune cells. Normally, the synovial fluid acts a lubricating, protective barrier and allows for smooth movement of bodily joints like the knees, hips, ankles, and fingers. When the tissue is attacked and degraded, however, the fluid loses its ability to lubricate and the bones begin rubbing against one other. This causes the severe pain and inflammation associated with arthritis.

Traditionally, individuals between the ages of 40 and 60 have been most prone to developing RA, even though it’s not necessarily a result of bodily wear and tear. For some reason (likely as a result of an internal molecular trigger), specialized T-cells in the body recognize the synovial tissue as “harmful,” and thus begin attacking it.

Other risk factors associated with rheumatoid arthritis include:

  • Sex (women are statistically three times more likely to develop the condition than men)
  • Genes (there is definitely a genetic factor associated with onset RA, though scientists are unclear what gene(s) are specifically involved)
  • Obesity (obese individuals are statistically proven to have significantly slowed metabolisms, which can promote inflammation of joint tissue, including tissues of the synovial membrane)

Also, rheumatoid factor is a specific antigen that has been recognized and associated with onset RA, though doctors and researchers are still unclear what exactly it does in terms of instigating immune cells to attack healthy joint tissue. Simple blood tests can show the presence (or lack thereof) of rheumatoid factor in most individuals, but this is not necessarily an indication that the individual will develop full blown rheumatoid arthritis.

In terms of conventional treatment, RA has most commonly been treated in the past with simple analgesics (pain relievers), including over-the-counter NSAID’s like Advil, Bayer, and ibuprofen in mild cases. For more severe cases, biologics and high strength pharmaceutical drugs called DMARD’s (disease-modifying anti-rheumatic drugs) are often necessary, though these medications (such as methotrexate) are dangerous in that they suppress the immune system, which rather drastically raises the possibility for infection.

Opioid painkillers are also a popular conventional treatment option for rheumatoid arthritis, but of course the dangerous risks associated with abuse, addiction, and overdose in these kinds of drugs are well-documented. For many thousands of users, CBD oil for arthritis is proving to be an incredibly effective alternative treatment option with negligible risks and practically zero side effects.

How CBD oil for rheumatoid arthritis works with the endocannabinoid system

In terms of functionality, it’s believed that CBD oil for rheumatoid arthritis may actually work by suppressing T-cell activity at the site of joint inflammation. This is different from conventional RA and OA treatments in that it may actual allow the underlying cause of the disease to be treated, rather than just the symptoms.

While the exact mechanisms are not fully understand, it’s recognized that T-cells likely play a crucial role in the onset of rheumatoid arthritis. For whatever reason, molecular triggers signal for the immune (T-cell) attack on healthy synovial tissue, thereby inducing the inflammation and subsequent pain associated with RA. If, as studies have shown, CBD oil is actually able to suppress this unnatural T-cell activity, researchers may be on to perhaps the only natural medication that’s actually able to treat the underlying cause of arthritis.

Additionally, it’s important to understand how CBD oil works to interact with the body’s own endocannabinoid system, or ECS. In short, the ECS is a vast network of naturally-occurring cannabinoids (just like CBD) and cannabinoid receptors. These receptors have been found all throughout the human body, including in the synovial tissue that’s targeted and attacked by immune cells in rheumatoid arthritis.

When a patient takes CBD oil, the ECS receptors are stimulated so as to be able to respond to the influx of new cannabinoids (which is the CBD oil). When the CBD binds to the receptors in the body, the substrate becomes active and begins working to regulate pain, suppress inflammation, and improve overall joint function.

And lastly, CBD oil is a well-known and very well-documented anti-inflammatory, so the majority of RA sufferers can expect to find significant joint pain relief when taking the medication, regardless of whatever internal mechanisms the cannabinoid may have on T-cells or the immune response.

What’s the best CBD oil for arthritis?

A lot of people like to use topical CBD oils, creams, and salves as rheumatoid arthritis treatment. These medications are fast-acting, and incredibly simple to use. All you do is massage the ointment into the affected area, and the active CBD compound is absorbed into the tissue where it begins interacting with receptors of the ECS.

Likewise, oral CBD tinctures are also effective at treating rheumatoid arthritis. These oils usually come in a dropper or spray bottle, and are administered sublingually (under the tongue). Absorptive tissues work to absorb the active CBD compounds, at which point they enter into the bloodstream and travel to the site of inflammation. This type of CBD oil usually takes longer to begin working, but patients can expect the effects and therapeutic relief to be longer-lasting than topical creams or ointments.

If you are looking for some great brands that develop excellent CBD oils and creams, check out our homepage. Each brand has been rated by price, quality and purity.

CBD oils that work

About the Author
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Jonathan Miller
Jonathan Miller, age 53 is an Ex Railyard Engineer who suffers from chronic back pain and anxiety. Jonathan’s goal was to create an unbiased site that would provide anyone who seeks help in CBD oil as a treatment, with accurate and helpful information.
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One response to “CBD Oil for Rheumatoid Arthritis [Understanding Endocannabinoids]”

  1. Hey Alison, check out You’ll find there a wide range of oils

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Getting Started with CBD Oil

If you suffer from anxiety (like me), depression or pain and are looking to get started with CBD oil, you need information on how to buy CBD oil, or you’re simply looking to learn more about CBD products, you’ve arrived at the right place.

What is CBD?

Cannabidiol, aka CBD, is a compound found in the cannabis plant that has significant medical benefits. CBD can be extracted from two different species of the Cannabis Sativa L plant, which include Cannabis and Hemp. Unlike its rival THC, CBD does not make people feel “stoned” and can actually counteract the psychoactivity of THC.

One of the main advantages of CBD is its non-psychoactive affect making it a great option for people looking for relief from inflammation, anxiety, insomnia, seizures, spasms, and other conditions.
As I mentioned above the primary distinction between Hemp and CBD oil is the part of the plant they are derived from and what parts of the plant are used to create the oil. Hemp oil is typically made from pressing cannabis seeds to extract the fatty oil from within, while some that have mastered the CBD extraction process also use the flowers as they contain high percentages of CBD. CBD oil, on the other hand, is usually made from the flowers of cannabis plant through various extraction methods.

How Does CBD Affect Your Body?

The way marijuana affects your body varies from person to person as it will often depend on genetics, tolerance to the cannabinoids, medical health, DNA, and more. It also depends on the way you consume the CBD, for example, the effects of vaping CBD are far different to smoking it in the form of high-CBD cannabis strains. 

CBD and the way it affects us is still of somewhat a mystery to researchers they still try to figure out how it effects the EndoCannabinoid system. During the previous century, it was discovered that our bodies have receptors within the brain and central nervous system. Specific cannabinoids such as CBD bind to those receptors and activate the EndoCannabinoid System (ECS). This then provides a wide range of psychological and physical benefits helping the body.

Without going into specifics, cannabinoids signal to the body to create endocannabinoids and build more receptors. This helps the body to limit things associated with pain and inflammation, repairs cells and provides a wide range of other health benefits. Unlike other cannabinoids, CBD is thought to be the ultimate anti-inflammatory cannabinoid.

Want to learn more about how CBD works read: How Long Does it Take CBD to Work

Medical Benefits of CBD

There is a misconception as to whether CBD can help treat patients, similar to pharmaceutical medicine, but thanks to the internet and a few different medical studies patients and researchers have been exposing their findings on how CBD oil is helping to cure a wide range of medical conditions.

The most popular story was the one of Charlotte Figi. At the time Charlotte was only 6 years old. As a little girl, she was experiencing over 300 epileptic seizures per week until she was successfully treated by a CBD-rich strain oil, later named Charlotte’s Web.

The high-quality CBD oil, changed her life, helping her to overcome a 6-year battle. Since her story hit the news, CBD and other cannabinoids of the cannabis plant are constantly being researched to understand how they can help to treat different medical conditions. As a matter of fact, CBD has been thought to help treat over 170 medical conditions, among them severe conditions such as Anorexia, Cancer, Arthritis, Depression, Anxiety, Chronic Pain, Insomnia, Glaucoma, multiple sclerosis and PTSD.

Recent studies have even shown that CBD, may cure life-threatening diseases by altering genes. Other studies have proven that it might even be an effective treatment for osteoarthritis and chronic pain.

The way that CBD works is that it interacts with receptors located in different parts of the central nervous system. These receptors are called CB1 and CB2. Both reflect the areas of the brain they interact with such as the limbic system. When taking CBD, this cannabinoid locks in on these receptors and affects the body in different ways. For example, it can help to block the pain caused by specific medical conditions.

While numerous studies have shown promising results, it is important to understand that CBD research is still at premature stages. A 2011 study that researched CBD for fibromyalgia showed extremely promising results. 56 of 112 participants who took CBD in the form of oil saw a great reduction in their symptoms and pain, while those using traditional methods didn’t see hardly any improvement.

Can you Buy CBD if you live in an illegal state?

The process is not cut-&-dry, and but thanks to the Farm Bill of 2014, forms of CBD can now be delivered to your doorstep. Those that live in recreational states can purchase CBD cannabis oil which is high in potency and extremely effective for helping to treat severe medical conditions, while those that live in other states that are not medical or recreational can benefit from CBD hemp oil. CBD Hemp oil is perfect for helping to treat a wide range of conditions including anxiety, depression and acute pain. 

Who is NaturalWellNessCBDOil?

My name is Jonathan, and I’ve created this loving resource that is packed with information about CBD oil. I am growing a community on Facebook and are constantly engaging with different people to help them make more informed decisions. I review products on a daily basis and provide unbiased reviews about some of the top CBD oil manufacturers. All the information on the site is FREE; I only ask that you help to share the information you find on the site with other people that are suffering. 

To your health and happiness.